With Magnetic Resonance
Angiography, doctors can get clear, detailed images of the
blood vessels surrounding the heart. These images help
doctors make a reliable diagnosis and recommend the right
treatment.
This procedure is reviewed by a physician with
expertise in the area presented and is further reviewed by committees
from the American College of Radiology (ACR) and the Radiological
Society of North America (RSNA), comprising physicians with expertise
in several radiologic areas.
FAQs
What is MR Angiography?
Magnetic
resonance imaging (MRI) is a method of producing extremely detailed
pictures of body tissues and organs without the need for x-rays. The
electromagnetic energy that is released when exposing a patient to
radio waves in a strong magnetic field is measured and analyzed by a
computer, which forms two- or three-dimensional images that may be
viewed on a TV monitor. MR angiography (MRA) is an MRI study of the
blood vessels. It utilizes MR technology to detect, diagnose and aid
the treatment of heart disorders, stroke and blood vessel diseases. MRA
provides detailed images of blood vessels without using any contrast
material, although today a special form of contrast usually is given to
make the MR images even clearer. The procedure is painless, and the
magnetic field is not known to cause tissue damage of any kind.
What are some common uses of the procedure?
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Many
patients with arterial disease now have it treated in the radiology
department rather than undergoing surgery in an operating room. MRA is
a very useful way of finding problems with blood vessels and
determining how to best to treat those problems.
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The
carotid arteries in the neck that conduct blood to the brain are a
common site of atherosclerosis, which may severely narrow or block off
an artery, reducing blood flow to the brain and even causing a stroke.
If an ultrasound study shows that such disease is present, many
surgeons now will do the necessary operation after confirmation by MRA,
dispensing with the need for catheter angiography.
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MRA
has found wide use in checking patients for diseased intracranial (in
the head) arteries, so that only those with positive findings will have
to have a more invasive catheter study.
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MRA also is used to detect disease in the aorta and in blood vessels supplying the kidneys, lungs and legs.
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Patients
with a family history of arterial aneurysm, a ballooning out of a
segment of the vessel wall, can be screened by MRA to see if they have
a similar disorder that has not produced symptoms. If an aneurysm is
found, it may be eliminated surgically, possibly avoiding serious or
fatal bleeding.
How should I prepare for the procedure?
The magnetic field used for MRA will pull on any iron-containing object
in the body, such as a heart pacemaker, intrauterine device, vascular
access port, metal plate, or pins, screws or staples. The radiologist
or technologist should know about any such item and also whether you
have ever had a bullet in your body, whether you ever worked with
metals, or if you have had a joint replacement. If there is any
question, an x-ray can be taken to detect metal objects. The
radiologist also should know if you have fillings in your teeth, which
could distort images of the facial region or brain. Braces make it
harder to properly adjust the MRI unit. You will be asked to remove
hairpins, jewelry, eyeglasses, hearing aids, and any dental work that
can be taken out. Some wigs contain metal and must be removed. Red dyes
used in tattoos and permanent eyeliner may contain metallic iron, but
this is rarely a problem. You should report any drug allergies to the
radiologist or technologist, and should mention if there's any
possibility that you might be pregnant.
You can eat normally before the exam (unless told differently), but a
young child should not eat or drink for about four hours if they will
receive a sedative. The rules vary at different MRI facilities, so be
sure to check with your medical center about eating and drinking before
the exam. Medications may be taken as usual. Some patients will feel
uncomfortably confined (claustrophobic) when enclosed in an MRI unit.
If necessary, you will be given a sedative to help put you at ease,
though probably less than one in every 20 patients will need this. You
will wear a lightweight medical gown for the exam.
What does the equipment look like?
The traditional MRI unit is a large tube surrounded by a circular
magnet, in which the patient lies without moving for several seconds at
a time. The patient is placed on a wheeled bed that is moved into the
magnet. In recent years patient-friendly units have been designed, and
examination in such units is becoming increasingly available. These
machines are both shorter and wider than a conventional MRI unit, and
do not fully enclose the patient. Some of the newer C-shaped units are
even open on all sides, and so are very attractive to patients who tend
toward claustrophobia. A drawback is that image quality is not as
consistently good.
How does the procedure work?
Exposing the patient to radio waves in a strong magnetic field
generates data that are used by a computer to create images of tissue
slices that may be viewed in any plane or from any direction. The
magnetic field lines up atomic particles called protons in the tissues,
which are then spun by a beam of radio waves and produce signals that
are picked up by a receiver in the scanner. It is these signals that
are processed by the computer to produce images. The resulting images
are very sharp and detailed, and so are able to detect tiny changes
from the normal pattern that are caused by disease or injury. Special
settings are used to image various structures, such as arteries in the
case of MRA.
How is the procedure performed?
The patient is placed on a special table and positioned inside the
opening of the MRI unit. A typical exam consists of two to six imaging
sequences, each taking from two to 15 minutes. Each sequence provides a
specific image orientation and a specified degree of image clarity or
contrast. Depending on the type of exam being done, the total time
needed can range from 10 to 60 minutes, not counting the time needed to
change clothing, have an IV put in, and answer questions. When contrast
material is needed, a substance called gadolinium is given by IV
injection during one of the imaging sequences. It highlights blood
vessels, making them stand out from surrounding tissues.
The radiologist and technologist leave the examining room during the
actual imaging process, but the patient can communicate with them at
any time using an intercom. Some centers permit a friend to stay
nearby, or a parent if a child is being examined. When the exam is
completed you will be asked to wait to make sure that more images are
not needed.
What will I experience during the procedure?
The technologist will make you as comfortable as possible, but at times
the magnet may be within a few inches of your face. For those who
become very uncomfortable when enclosed in a small space, a mild
sedative is nearly always effective. You may notice a warm feeling in
the area being studied. This is normal, but do not hesitate to report
it if it bothers you. If you receive a contrast material injection
there may be some local discomfort at the IV site. The loud tapping or
knocking noises that are heard during certain parts of the exam disturb
some patients; earplugs may help.
Who interprets the results and how do I get them?
A radiologist experienced in MRI will analyze the results and send a
report to your physician, along with an interpretation of the findings.
Your physician in turn will discuss the MRA findings with you. Some
centers now send diagnostic reports and images over the Internet,
speeding up the process.
What are the benefits vs. risks?
Benefits
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Detailed
images of blood vessels and blood flow are obtained without having to
insert a catheter directly into the area of interest, so that there is
no risk of damaging an artery.
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The procedure itself and the time needed to recover are shorter than after a traditional catheter angiogram.
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MRA is less costly than catheter angiography.
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There is no exposure to x-rays during an MRI study.
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Contrast
material may be injected, but unlike catheter angiography or CT
angiography, which make use of iodine-based contrast material, the risk
of an allergic reaction from MRA contrast is extremely low and kidney
damage does not occur. Even without using contrast material, MRA can
provide high-quality images of many blood vessels, making it very
useful for patients prone to allergic reactions.
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As
with catheter-based angiography or CT angiography, it frequently is
possible to defer surgery after getting the results of an MRA study. If
surgery remains necessary, it can be performed more accurately.
Risks
There are no definite side effects from any type of MRI study including
MR angiography. Claustrophobia may be a problem, however. When it is
severe and not relieved by giving a sedative, an alternative imaging
method may have to be tried. If a metal implant is present but goes
undetected, it may be affected by the strong magnetic field to which
the patient is exposed. In addition, if the implant is close to the
examination site it may be hard to get high-quality images.
MRI generally is avoided during the first three months of pregnancy.
Ultrasound is preferred at this time unless the woman might have a very
serious condition that is best detected by MRA. The effects of MRI on
the fetus, if any, remain to be determined. The general rule for MR
imaging and other diagnostic studies in pregnancy is that they should
be avoided unless there is substantial risk from missing the correct
diagnosis because the procedure is not done. Women who are
breast-feeding should inform the radiologist and ask how to proceed.
They may pump breast milk before the exam for use until gadolinium
contrast material has cleared from the body.
What are the limitations of MR Angiography?
MRA does not image calcium, as does CT angiography. The procedure
should be avoided in any patient having a pacemaker, implanted
neurostimulator, metallic ear implant, or metallic object within the
eye socket. It should also be avoided if there is a bullet fragment or
if the patient has a port for delivering insulin or chemotherapy. For
patients who are very claustrophobic, adequate nursing staff must be on
hand to monitor sedation.
The clearness of MRA images does not match those obtained by
conventional angiography. Furthermore, images are acquired more slowly
by MRA than by catheter angiography. Sometimes it may be difficult to
separate images of arteries from veins by MRA.